ea0099p2 | Adrenal and Cardiovascular Endocrinology | ECE2024
Webb Susan
, Santos Alicia
, Aulinas Maso Anna
, Tomsic Karin Zibar
, Amaral Claudia
, Feelders Richard
, Ragnarsson Oskar
, Ferrante Emanuele
, Ceccato Filippo
, Chabre Olivier
, Cristante Justine
, Hanzu Felicia
, Reincke Martin
, Chanson Philippe
, Tabarin Antoine
, Sequeira Duarte Joao
, Guelho Daniela
, Fajardo Carmen
, Bostnavaron Martine
, Bou Nader Myriam
, Bertherat Jerome
, Brue Thierry
Background: Ketoconazole is a steroidogenesis inhibitor approved in Europe for the treatment of endogenous Cushings syndrome (CS) based on retrospective studies published over 3 decades. We present interim data from the first prospective observational, multicenter, international study on ketoconazole, a non-interventional PASS (Post-Authorization Safety study) requested by EMA at the time of registration to confirm ketoconazole good tolerance and effectiveness. This stud...